In VS2005 after I saved my project, the next time I opened it, the main form
was missing all its controls.  I had placed 3 buttons and a label on the
form and the project had been running successfully.  I did some
investigation and determined that there were 4 lines of code missing from
the Designer.cs which caused the controls to not appear.  The 4 lines of
code missing were:

this.Controls.Add(this.btnGo);
this.Controls.Add(this.GoClientRE);
this.Controls.Add(this.btnClose);
this.Controls.Add(this.label1);

Once I added these lines back in and rewired the event handlers, everything
worked fine as before.  Any ideas what may have caused this?