FWIW: I don't know for sure.

I can tell you that MS has not shipped a 16 bit development tool in about a
decade. That said, I would expect that the command line tools work. I would
be quite surprised if you could get either PWB or the IDE to work.

I can tell you that I keep the 16 bit compiler on an XP/SP2 box here just
for giggles. I just used it to compile and link K&R's famous hello world
program. The compiler is reports version 8.0c and a copyright date of 1993.
I think it is the one that shipped with Visual C++ 1.52C. In any event, the
test compiled, linked and ran successfully.

Regards,
Will