Sounds like you are using the default instance of the form.  So either create
your own instance each time you need the form or add a public DoRefresh
method to your form (which would reset the form to its initial values) and
call it right before you use (show) the form each time.

Check to see where you form is being dim'd
it might look something like this:
DIM fbla AS Form

you most likley are missing the "NEW" parameter.

DIM fbla AS NEW Form

If the values are global setting, you wanna save those for next running,
please bind the value to ApplicationSettings. All settings will be saved to
and reloaded from your app.config automatically.

If you just want to save those in one instance, there are 2 ways to deal
with it.
1 Create a module or static class and define all value you need with saving
all of that while closing that form. When re-open it, just reload that from
those value by your code.
2 Create a module or static class to hold the define of that form (Dim xxx
As Form1). Use xxx.Hide to hide your form instead of closing it. And Use
xxx.Show to reopen it.