Have you tried using cellspacing for the radiobuttonlist?
I mean something like
<asp:RadioButtonList ID="RadioBtnList" runat="server" RepeatColumns="2"
CellSpacing="10">
<asp:ListItem>Item 1</asp:ListItem>
<asp:ListItem>Item 2</asp:ListItem>
<asp:ListItem>Item 3</asp:ListItem>
<asp:ListItem>Item 4</asp:ListItem>
<asp:ListItem>Item 5</asp:ListItem>
<asp:ListItem>Item 6</asp:ListItem>
</asp:RadioButtonList>
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>Jerry

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